diff --git a/CMakeLists.txt b/CMakeLists.txt
index df89060d..055c3ca9 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -27,7 +27,7 @@ option(BUILD_SHARED_LIBS "Build shared instead of static library" ${PROJECT_IS_T
 option(UNICORN_FUZZ "Enable fuzzing" OFF)
 option(UNICORN_BUILD_TESTS "Build unicorn tests" ${PROJECT_IS_TOP_LEVEL})
 option(UNICORN_INSTALL "Enable unicorn installation" ${PROJECT_IS_TOP_LEVEL})
-set(UNICORN_ARCH "x86;arm;aarch64;riscv;mips;sparc;m68k;ppc" CACHE STRING "Enabled unicorn architectures")
+set(UNICORN_ARCH "x86;arm;aarch64;riscv;mips;sparc;m68k;ppc;s390x" CACHE STRING "Enabled unicorn architectures")
 option(UNICORN_TRACER "Trace unicorn execution" OFF)
 
 foreach(ARCH_LOOP ${UNICORN_ARCH})