diff --git a/target/mips/translate.c b/target/mips/translate.c
index 3197a692c4..c64a1bc42e 100644
--- a/target/mips/translate.c
+++ b/target/mips/translate.c
@@ -31442,8 +31442,8 @@ static void mips_tr_init_disas_context(DisasContextBase *dcbase, CPUState *cs)
 #else
         ctx->mem_idx = hflags_mmu_index(ctx->hflags);
 #endif
-    ctx->default_tcg_memop_mask = (ctx->insn_flags & ISA_MIPS32R6) ?
-                                  MO_UNALN : MO_ALIGN;
+    ctx->default_tcg_memop_mask = (ctx->insn_flags & (ISA_MIPS32R6 | ISA_MIPS64R6 |
+                                  INSN_LOONGSON3A)) ? MO_UNALN : MO_ALIGN;
 
     LOG_DISAS("\ntb %p idx %d hflags %04x\n", ctx->base.tb, ctx->mem_idx,
               ctx->hflags);