diff --git a/stmhal/i2c.c b/stmhal/i2c.c
index e818ec380f..a3ded36ec0 100644
--- a/stmhal/i2c.c
+++ b/stmhal/i2c.c
@@ -760,12 +760,14 @@ STATIC mp_obj_t pyb_i2c_send(mp_uint_t n_args, const mp_obj_t *pos_args, mp_map_
         if (!use_dma) {
             status = HAL_I2C_Master_Transmit(self->i2c, i2c_addr, bufinfo.buf, bufinfo.len, args[2].u_int);
         } else {
+            MP_HAL_CLEAN_DCACHE(bufinfo.buf, bufinfo.len);
             status = HAL_I2C_Master_Transmit_DMA(self->i2c, i2c_addr, bufinfo.buf, bufinfo.len);
         }
     } else {
         if (!use_dma) {
             status = HAL_I2C_Slave_Transmit(self->i2c, bufinfo.buf, bufinfo.len, args[2].u_int);
         } else {
+            MP_HAL_CLEAN_DCACHE(bufinfo.buf, bufinfo.len);
             status = HAL_I2C_Slave_Transmit_DMA(self->i2c, bufinfo.buf, bufinfo.len);
         }
     }
@@ -834,12 +836,14 @@ STATIC mp_obj_t pyb_i2c_recv(mp_uint_t n_args, const mp_obj_t *pos_args, mp_map_
         if (!use_dma) {
             status = HAL_I2C_Master_Receive(self->i2c, i2c_addr, (uint8_t*)vstr.buf, vstr.len, args[2].u_int);
         } else {
+            MP_HAL_CLEANINVALIDATE_DCACHE(vstr.buf, vstr.len);
             status = HAL_I2C_Master_Receive_DMA(self->i2c, i2c_addr, (uint8_t*)vstr.buf, vstr.len);
         }
     } else {
         if (!use_dma) {
             status = HAL_I2C_Slave_Receive(self->i2c, (uint8_t*)vstr.buf, vstr.len, args[2].u_int);
         } else {
+            MP_HAL_CLEANINVALIDATE_DCACHE(vstr.buf, vstr.len);
             status = HAL_I2C_Slave_Receive_DMA(self->i2c, (uint8_t*)vstr.buf, vstr.len);
         }
     }
@@ -920,6 +924,7 @@ STATIC mp_obj_t pyb_i2c_mem_read(mp_uint_t n_args, const mp_obj_t *pos_args, mp_
         dma_init(&rx_dma, self->rx_dma_descr, self->i2c);
         self->i2c->hdmatx = NULL;
         self->i2c->hdmarx = &rx_dma;
+        MP_HAL_CLEANINVALIDATE_DCACHE(vstr.buf, vstr.len);
         status = HAL_I2C_Mem_Read_DMA(self->i2c, i2c_addr, mem_addr, mem_addr_size, (uint8_t*)vstr.buf, vstr.len);
         if (status == HAL_OK) {
             status = i2c_wait_dma_finished(self->i2c, args[3].u_int);
@@ -988,6 +993,7 @@ STATIC mp_obj_t pyb_i2c_mem_write(mp_uint_t n_args, const mp_obj_t *pos_args, mp
         dma_init(&tx_dma, self->tx_dma_descr, self->i2c);
         self->i2c->hdmatx = &tx_dma;
         self->i2c->hdmarx = NULL;
+        MP_HAL_CLEAN_DCACHE(bufinfo.buf, bufinfo.len);
         status = HAL_I2C_Mem_Write_DMA(self->i2c, i2c_addr, mem_addr, mem_addr_size, bufinfo.buf, bufinfo.len);
         if (status == HAL_OK) {
             status = i2c_wait_dma_finished(self->i2c, args[3].u_int);
diff --git a/stmhal/mphalport.h b/stmhal/mphalport.h
index 7521024020..77cb0204d0 100644
--- a/stmhal/mphalport.h
+++ b/stmhal/mphalport.h
@@ -10,8 +10,8 @@
 #define MP_HAL_CLEAN_DCACHE(addr, size)
 #elif defined(MCU_SERIES_F7)
 #define MP_HAL_UNIQUE_ID_ADDRESS (0x1ff0f420)
-#define MP_HAL_CLEANINVALIDATE_DCACHE(addr, size) (SCB_CleanInvalidateDCache_by_Addr((uint32_t*)((uint32_t)addr & ~0x1f), ((uint32_t)(addr + size + 0x1f) & ~0x1f) - ((uint32_t)addr & ~0x1f)))
-#define MP_HAL_CLEAN_DCACHE(addr, size) (SCB_CleanDCache_by_Addr((uint32_t*)((uint32_t)addr & ~0x1f), ((uint32_t)(addr + size + 0x1f) & ~0x1f) - ((uint32_t)addr & ~0x1f)))
+#define MP_HAL_CLEANINVALIDATE_DCACHE(addr, size) (SCB_CleanInvalidateDCache_by_Addr((uint32_t*)((uint32_t)addr & ~0x1f), ((uint32_t)((uint8_t*)addr + size + 0x1f) & ~0x1f) - ((uint32_t)addr & ~0x1f)))
+#define MP_HAL_CLEAN_DCACHE(addr, size) (SCB_CleanDCache_by_Addr((uint32_t*)((uint32_t)addr & ~0x1f), ((uint32_t)((uint8_t*)addr + size + 0x1f) & ~0x1f) - ((uint32_t)addr & ~0x1f)))
 #elif defined(MCU_SERIES_L4)
 #define MP_HAL_UNIQUE_ID_ADDRESS (0x1fff7590)
 #define MP_HAL_CLEANINVALIDATE_DCACHE(addr, size)